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Research-informed health explainers

Plain-language guides to conditions, treatments, and medications — each one grounded in peer-reviewed research from the specialists in our directory.

18 articles in Endocrinology · Page 2 of 2

EndocrinologyApr 11, 2026

SELECT Trial: Semaglutide and Heart Attack Risk

What the SELECT trial showed about semaglutide reducing heart attacks, strokes, and cardiovascular death in people with obesity but no diabetes.

Ildiko Lingvay, MD · Anne Peters, M.D. · Janet McGill, MD

EndocrinologyApr 11, 2026

Semaglutide vs Tirzepatide: Diabetes and Weight Loss

How semaglutide and tirzepatide compare for type 2 diabetes and weight loss: A1c reduction, weight outcomes, cardiovascular data, and when each is the better choice.

Ildiko Lingvay · Bruce Bode · Kathleen Dungan · John Buse

EndocrinologyApr 11, 2026

Semaglutide vs tirzepatide for weight loss

Comparing semaglutide and tirzepatide for weight loss: what the clinical trials show, who each drug is typically for, and what to ask your doctor.

Ildiko Lingvay · John Buse · Caroline Apovian

EndocrinologyApr 11, 2026

Total vs Partial Thyroidectomy for Graves Disease

Evidence-based comparison of total and partial thyroidectomy for Graves disease: cure rates, recurrence risk, complications, and when each approach is recommended.

Marius Stan, M.D. · Giuseppe Barbesino, MD · Ellen Marqusee, MD · Megan Haymart, M.D.

EndocrinologyApr 11, 2026

Transsphenoidal vs Craniotomy for Pituitary Tumor

For most pituitary tumors, transsphenoidal surgery through the nose is the standard approach. Craniotomy is reserved for specific cases. Here is what the evidence shows.

Beverly Biller, MD · Laurence Katznelson, MD · Maria Fleseriu, MD · Baha Arafah, MD

EndocrinologyApr 11, 2026

Weight Regain After Stopping GLP-1: What to Expect

Most people regain significant weight after stopping GLP-1 medications. Here is what the evidence shows, why it happens, and how to reduce regain.

Ildiko Lingvay, MD · Anne Peters, M.D. · Janet McGill, MD