Research-informed health explainers
Plain-language guides to conditions, treatments, and medications — each one grounded in peer-reviewed research from the specialists in our directory.
35 articles · Page 1 of 3
Ablation vs Medication for AFib: Which Is Better?
Plain-language comparison of catheter ablation and antiarrhythmic medication for atrial fibrillation, grounded in the CABANA trial and landmark electrophysiology research.
Douglas Packer, M.D. · Hugh Calkins, M.D. · Edward Gerstenfeld, MD
Academic vs Community Cancer Care: Which Is Better?
Choosing between an academic cancer center and a community oncologist? What the research shows about when each setting produces better outcomes.
Julie Sosa, MD · Jennifer Temel, MD · Ramaswamy Govindan, MD · Al Benson, MD
Botox vs CGRP Injections for Migraines: Key Differences
Plain-language comparison of onabotulinumtoxinA (Botox) and CGRP monoclonal antibodies for chronic migraine prevention, with evidence from landmark trials.
Peter Goadsby, MD · Charles Argoff, MD · Richard Lipton, MD
Catheter Ablation vs Open-Heart Surgery for AFib
Plain-language comparison of catheter ablation and surgical maze for atrial fibrillation, grounded in peer-reviewed research from leading electrophysiologists.
Hugh Calkins, M.D. · Edward Gerstenfeld, MD · Douglas Packer, M.D.
CGRP Injections for Migraine: How Effective Are They Really?
A plain-language guide to CGRP monoclonal antibody injections for migraine prevention, grounded in the peer-reviewed research of leading headache specialists.
Peter Goadsby, MD · Stephen Silberstein, M.D. · Richard Lipton, MD
Chemo-Induced Peripheral Neuropathy: Treatment Options
Evidence-based guide to chemotherapy-induced peripheral neuropathy (CIPN) — what causes it, which chemotherapy agents are highest risk, what treatment options exist, and what recovery looks like.
Ahmet Hoke, M.D. · Michael Rowbotham, M.D. · Eva Feldman, MD
Chronic Daily Headache: Causes and How to Break the Cycle
Evidence-based explainer on the four types of chronic daily headache, the mechanisms that perpetuate them, and the treatment approaches most likely to work.
David Borsook, MD PHD · Richard Lipton, MD · Charles Argoff, MD
CIDP vs Guillain-Barré Syndrome: Key Differences
Plain-language comparison of CIDP and GBS — two autoimmune demyelinating neuropathies — including how they are diagnosed and how treatment differs based on time course.
Thomas Brannagan, MD · Michael Rowbotham, M.D. · Eva Feldman, MD
Diabetic Neuropathy Progression: How to Slow It Down
Evidence-based guide to the factors that drive diabetic neuropathy progression and the interventions — glucose control, exercise, and lifestyle — with the strongest evidence for slowing it.
Rodica Busui, MD, PHD · Eva Feldman, MD · Brian Callaghan, MD
Gabapentin vs Pregabalin for Neuropathic Pain: Key Differences
Evidence-based comparison of gabapentin and pregabalin for neuropathic pain, including efficacy data, dosing differences, side effects, and when each is preferred.
Michael Rowbotham, M.D. · Eva Feldman, MD · Charles Argoff, MD
GLP-1 for PCOS: Does It Help?
GLP-1 medications are not FDA-approved for PCOS, but emerging evidence supports off-label use in women with overweight and insulin resistance — the metabolic drivers of PCOS symptoms.
Ildiko Lingvay, MD · Anne Peters, M.D. · Kenneth Cusi, MD
GLP-1 Side Effects: How to Manage Nausea and Vomiting
Nausea is the top reason people stop GLP-1 medications. Here is what the STEP trials found and how to manage it.
Ildiko Lingvay, MD · Anne Peters, M.D. · John Buse, MD